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Medicinal Chemistry of Nucleic Acids

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  • Author(s)Li-He Zhang / Zhen Xi / Jyoti Chattopadhyaya / Sidney M. Hecht
  • Edition1
  • Published11th August 2011
  • PublisherJohn Wiley & Sons Inc (US)
  • ISBN
Complete, up-to-date coverage of the broad area of nucleic acid
chemistry and biology

Assembling contributions from a collection of authors with
expertise in all areas of nucleic acids, medicinal chemistry, and
therapeutic applications, Medicinal Chemistry of Nucleic
Acids
presents a thorough overview of nucleic acid
chemistry?a rapidly evolving and highly challenging
discipline directly responsible for the development of antiviral
and antitumor drugs. This reliable resource delves into a multitude
of subject areas involving the study of nucleic acids?such as
the new advances in genome sequencing, and the processes for
creating RNA interference (RNAi) based drugs?to assist
pharmaceutical researchers in removing roadblocks that hinder their
ability to predict drug efficacy. Offering the latest cutting-edge
science in this growing field, Medicinal Chemistry of Nucleic Acids
includes:




  • In-depth coverage of the development and application of modified
    nucleosides and nucleotides in medicinal chemistry




  • A close look at a large range of current topics on nucleic acid
    chemistry and biology




  • Essential information on the use of nucleic acid drugs to treat
    diseases like cancer




  • A thorough exploration of siRNA for RNAi and the regulation of
    microRNA, non-coding RNA (ncRNA), a newly developing and exciting
    research area




Thorough in its approach and promising in its message,
Medicinal Chemistry of Nucleic Acids probes the new domains
of pharmaceutical research?and exposes readers to a wealth of
new drug discovery opportunities emerging in the dynamic field of
nucleic acid chemistry.

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