Scientific Principles and Clinical Practice
This new textbook has an international authorship and is a
practical, up-to-date resource for clinicians responsible for the
care of children with oncologic and malignant hematologic disease.
It is specifically designed for practicing oncologists and
hematologists, pediatricians with an interest in childhood cancer
and trainees seeking a systematic approach to these disorders.
This new textbook has an emphasis on the visual presentation
and ease of reading of contemporary and comprehensive information
for children?s cancers and contains detailed tables, fact
boxes and illustrations.
The textbook begins with an introduction to the general
principles of the scientific foundation and treatment of childhood
cancers and hematological malignancies. Separate sections are
then devoted to descriptions of central nervous system tumors,
hematological malignancies and solid tumors of childhood which
encompass epidemiology, cellular and molecular biology, cancer
genetics, immunology, pharmacology and the findings of clinical
trials. For each area of science covered, key original references
and reviews are highlighted to direct further reading.
Diagnostic, biological, and therapeutic issues are integrated
into each tumor-specific chapter, with evidence supporting the
current rationales for risk stratification and the development of
novel therapies. A final section then explores supportive care,
palliative care, late effects considerations and psychosocial
issues as relate to children?s cancer.