Basic and Clinical Aspects
Von Willebrand Disease: Basic and Clinical Aspects
an insight into all aspects of the condition. Since its discovery,
von Willebrand disease has been extensively studied and the
causative factor deficiency, the understanding of the condition and
its treatment has greatly improved. This book summarizes recent
research and will help to optimize the management of patients with
von Willebrand disease.
This valuable book describes the important and complex role of
von Willebrand factor in hemostasis and thrombosis. In addition to
the current understanding of its molecular biology, this book gives
particular focus to the association between genetic variants of von
Willebrand factor and different von Willebrand disease phenotypes.
It also reviews the important area of the obstetric and
gynecological manifestations of von Willebrand disease, as well as
the treatment of acute bleeding.
Written by an international team of contributors it describes
the progress in, and difficulties of diagnosing phenotypes and
genotypes. Molecular diagnosis of type 1, type 2 and its subgroups,
and type 3 von Willebrand disease are presented as well as
discussion of the potential future role of gene therapy.
Von Willebrand Disease: Basic and Clinical Aspects is a
valuable resource for hematologists in practice and in training,
and specialists in thrombosis and hemostasis.